The xanthine alkaloids—caffeine, theobromine, and theophylline—are closely related compounds found in a variety of plants indigenous to several continents. Hopefully, this study guide can help make that process easier for you. 5. It is the responsibility of the Respiratory Therapist to learn about the drug class. We also have a guide on Adrenergic Bronchodilators that I think you will enjoy. ... Bronchodilators: Beta-Agonists Mechanism of Action. Bronchodilators work through their direct relaxation effect on airway smooth muscle cells. 19) • Prototype Drugs: – Theophylline-Theo-dur – Aminophylline . Specific xanthine agents. Indications are based on acute and chronic pulmonary disease and dysfunction. • Relieve Bronchoconstriction • Cause bronchodilatation . Learn faster with spaced repetition. Decreased pulmonary function B. Read more about the prescription drug XANTHINE DERIVATIVES - ORAL. Mechanism of Action Cushley MJ, Holgate ST. Bronchodilators Xanthine derivatives Beta-agonists Anticholinergics Antileukotriene agents Corticosteroids Mast cell stabilizers Sympathomimetic Agents ie epi, ephedrine, isoproterenol, terbutaline. When administering the methylxanthine theophylline, the nurse can expect: A. Study asthma - bronchodilator Xanthine drugs flashcards from georgie mair's bristol university class online, or in Brainscape's iPhone or Android app. Consumer information about the medication XANTHINE DERIVATIVES - ORAL , includes side effects, drug interactions, recommended dosages, and storage information. Theophylline (dimethylxanthine) has been used to treat airway diseases for more than 80 years. Xanthine Derivatives (Refer to Prototype List in syllabus, pg. The nurse instructs the client to limit the intake of xanthine-containing foods such as chocolate, cola, cocoa, tea, and coffee. Bronchodilators: ü Xanthines Derivatives . Medscape's clinical reference is the most authoritative and accessible point-of-care medical reference for physicians and healthcare professionals, available online and via all major mobile devices. Option D: Theophylline is a methylxanthine bronchodilator. The topic of Xanthine Medications will likely be covered in the Pharmacology courses of your school program. Theophylline is related chemically to the natural metabolite xanthine, which is a precursor of uric acid. BRONCHODILATOR CLASSIFICATIONS. Figure 8-1 shows the general xanthine structure and the structures of theophylline (1,3-dimethylxanthine) and caffeine (1,3,7-trimethylxanthine). at present, three major classes of bronchodilators, β(2)-adrenoceptor (AR) agonists, muscarinic receptor antagonists, and xanthines are available and can be used individually or in combination. Begins at the specific receptor stimulated All content is free. 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